Maternal Floor Infarction Wikipedia

It is formally known as placental maternal floor infarction it is also known as massive perivillous fibrin deposition.

Maternal floor infarction wikipedia.

By now everyone agrees that maternal floor infarction is a misnomer at least for most of the cases so labeled. The disease is characterized by extensive fibrin deposition in the intervillous spaces. Small placental infarcts especially at the edge of the placental disc are considered to be normal at term large placental infarcts are associated with vascular abnormalities e g. Micrograph of a placental infarct.

To understand the lesion the conditions in which perivillous fibrinoid forms must also be understood. Organization dedicated to. The pathology is a diffuse increase in peri inter villous fibrinoid and usually with some intervillous thrombi. Maternal floor infarction abbreviated mfi is a pathology of the placenta.

A pathologic entity characterised by deposition of fibrinoid material in the maternal surface and intervillous spaces of the placenta and which is associated with significant perinatal morbidity and mortality including stillbirth recurrent pregnancy loss premature delivery intrauterine growth restriction and. In this study of mfi and the related placental disorder massive perivillous fibrin deposition mfd semiquantitative histologic criteria for these diagnoses are defined and rates of iugr and recurrence are assessed. In october shortly after i found out the diagnosis of maternal floor infarction massive perivillous fibrin deposition basically huge clots formed around the villi the little fingerlike placental protusions that delivered nutrients to luke making them unable to function i connected with the folks over at the star legacy foundation the only national u s. Maternal floor infarction mfi is an uncommon placental disease associated with recurrent third trimester fetal loss and intrauterine growth retardation iugr usually severe.

In an attempt to determine the frequency course and outcome of maternal floor infarcts 39 215 placentas and pregnancies were reviewed. A maternal floor infarction then should show fibrin or matrix thickening of the maternal surface with otherwise typical changes of infarction in the villi. Maternal floor infarction mfi is a poorly understood placental lesion reportedly associated with intrauterine growth restriction iugr and recurrence. It is moot whether such a lesion which i will call true maternal floor infarction occurs but the term maternal floor infarction is not usually used in this sense.

A placental infarction results from the interruption of blood supply to a part of the placenta causing its cells to die.