Mesenchymal Stem Cell Therapy For Psoriasis

For this reason they are currently under investigation in clinical trials for the treatment of several autoimmune systemic disorders.

Mesenchymal stem cell therapy for psoriasis.

Mesenchymal stem cells mscs have recently been shown to have not only regenerative capabilities but also immunomodulating properties. The most common form plaque psoriasis appears most often as red scaly patches that itch and bleed. Nowadays mesenchymal stem cell mscs based therapy has become a promising therapeutic field which is expected to help in the treatment of the most costly and incurable diseases. Literature with regard to msc based strategies for the treatment of psoriasis.

Psoriasis can occur on any part of the body eyelids ears mouth and lips skin folds hands and feet arms and legs torso and nails. The specific stem cells that have proven useful in healing these skin lesions are mesenchymal stem cells and hematopoietic stem cells. Psoriasis is a chronic relapsing inflammatory disease affecting 2 3 of the population and is considered to be a systemic disease rather than one limited to the skin. 2 the pathogenesis of psoriasis has an immunological basis.

Treatment of psoriasis with mesenchymal stem cells to the editor. Here we explored the feasibility of using human umbilical cord derived msc huc msc infusion as a. Indeed according to the researchers psoriasis patients who have undergone bone marrow stem cells transplants have also gone. The skin at each of these sites is different and requires different treatments.

The anti inflammatory and immunomodulatory properties of mesenchymal stem cells mscs have been proposed to be involved in some autoimmune diseases and have been successfully tested in patients and mice. 1 here we report 2 cases of psoriasis vulgaris treated by umbilical cord derived mesenchymal stem cells uc mscs. For this reason they are currently under investigation in clinical trials for the treatment of several autoimmune systemic disorders. Current treatments including newly emerged biologic agents have some limitations 1 here we report 2 cases of psoriasis vulgaris treated by umbilical cord derived mesen.

However there is potential for other stem cell types to help with psoriasis as well. Mesenchymal stem cells mscs have recently been shown to have not only regenerative capabilities but also immunomodulating properties. By conduction a review of the existing literature on. Psoriasis is an incurable immune mediated disease which affects approximately 2 of the world s population.

1 the treatment varies depending on disease severity from topical agents and phototherapy to conventional immunosuppressant drugs and biologic agents. In these 2 cases both of the patients remained relapse free for 4 or 5 years. Psoriasis is a systemic immun.